Science & Research

ProLon’s state of the art research and development and pre-clinical and clinical trials were conducted at the University of Southern California’s Longevity Institute and Diabetes and Obesity Research Institute, and sponsored by the National Cancer Institutes (NCI) and National Institute on Aging (NIA) of the National Institute of Health (NIH).

The results of the above research were published in top scientific peer-reviewed journals.

Scientific Articles

Cell Metabolism

Feb 4, 2015

Fasting: Molecular Mechanisms and Clinical Applications

Science Translational Medicine

February 2017

Fasting-mimicking diet and markers/risk factors for aging, diabetes, cancer, and cardiovascular disease.

Cell Press

August 2016

Enhancing stem cell transplantation with “Nutri-technology”.


August 2016

Association of Animal and Plant Protein Intake With All-Cause and Cause-Specific Mortality

Cell Press

July 2016

Fasting-Mimicking Diet Reduces HO-1 to Promote T Cell-Mediated Tumor Cytotoxicity.

Biomed Central

June 2016

Dietary Interventions, Cardiovascular Aging, and Disease Animal Models and Human Studies

Circulation Research

May 2016

Dietary Interventions, Cardiovascular Aging, and Disease Animal Models and Human Studies

Cell Press

May 2016

A Diet Mimicking Fasting Promotes Regeneration and Reduces Autoimmunity and Multiple Sclerosis Symptoms.

Cell Metabolism

July 7, 2015

A periodic diet that mimics fasting and promotes multi-system regeneration, enhanced cognitive performance, and health span.

Aging Cell

March 11, 2013

Protein restriction cycles reduce IGF-1 and phosphorylated Tau, and improve behavioral performance in an Alzheimer’s disease mouse model.


February 21, 2013

Short-term calorie and protein restriction provide partial protection from chemotoxicity but do not delay glioma progression.


September 11, 2012

Fasting enhances the response of glioma to chemo- and radiotherapy.